Niklas Rye Jørgensen

Niklas Rye Jørgensen

Clinical Professor

Member of:

  • Clinical Biochemistry


  1. 2020
  2. Published
  3. Published

    Glucose-Dependent Insulinotropic Polypeptide (GIP) Reduces Bone Resorption in Patients With Type 2 Diabetes

    Christensen, Mikkel Bring, Lund, A. B., Jørgensen, Niklas Rye, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Journal of the endocrine society. 4, 9, 9 p., 097.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Harmonization of commercial assays for PIN: the way forward

    Vasikaran, S. D., Bhattoa, H. P., Eastell, R., Heijboer, A. C., Jørgensen, Niklas Rye, Makris, K., Ulmer, C., Kanis, J. A., Cooper, C., Silverman, S. & Cavalier, E., 2020, In: Osteoporosis International. 31, 3, p. 409-412

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Human P2X7 Receptor Causes Cycle Arrest in RPMI-8226 Myeloma Cells to Alter the Interaction with Osteoblasts and Osteoclasts

    Agrawal, A., Kruse, L. S., Vangsted, Annette Juul, Gartland, A. & Jørgensen, Niklas Rye, 2020, In: Cells. 9, 11

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Hypophosphatemic Hypovitaminosis D Induces Osteomalacia in the Adult Female Rat

    Durup, D., Diaz-delCastillo, M., Morgenlykke, J., Jensen, Lars Thorbjørn, Frandsen, E., Abelson, Klas, Pedersen, L., Lykkesfeldt, Jens, Ding, M., Jørgensen, Niklas Rye, Syberg, S., Petersen, S. & Heegaard, Anne-Marie, 2020, In: Endocrinology. 161, 8, bqaa100.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Interleukin-6 May Not Affect Bone Resorption Marker CTX or Bone Formation Marker P1NP in Humans

    Lehrskov, L. L., Kjeldsen, Sasha Alexandra Sampson, Lyngbæk, M. P., Chirstensen, R. H., Wedell-Neergaard, A., Søderlund, L., Jørgensen, Niklas Rye, Krogh-Madsen, Rikke, Albrechtsen, Nicolai Jacob Wewer & Ellingsgaard, H., 2020, In: Endocrine Research. 4, 9, 12 p., bvaa093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Inulin and milk mineral fortification of a pork sausage exhibits distinct effects on the microbiome and biochemical activity in the gut of healthy rats

    Thøgersen, R., Castro-Mejía, J. L., Sundekilde, U. K., Hansen, Lars Hestbjerg, Gray, N., Kuhnle, G., Jørgensen, Niklas Rye, Hansen, Axel Kornerup, Nielsen, Dennis Sandris & Bertram, H. C., 2020, In: Food Chemistry. 331, 10 p., 127291.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Low plasma levels of calcitonin gene-related peptide in persistent post-traumatic headache attributed to mild traumatic brain injury

    Ashina, H., Al-Khazali, H. M., Iljazi, A., Ashina, Sait, Jørgensen, Niklas Rye, Amin, Faisal Mohammad, dlt446, dlt446 & Schytz, Henrik Winther, 2020, In: Cephalalgia. 40, 12, p. 1276-1282 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    S100B and NSE in Cluster Headache – Evidence for Glial Cell Activation?

    Snoer, A. H., Vollesen, A. L. H., Beske, R. P., Guo, S., Hoffmann, J., Jørgensen, Niklas Rye, Martinussen, Torben, dlt446, dlt446 & Jensen, Rigmor Højland, 2020, In: Headache. 60, 8, p. 1569-1580 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Secretion of parathyroid hormone may be coupled to insulin secretion in humans

    Sass, M. R., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hare, Kristine Juul, Borbye-Lorenzen, N., Kiss, K., Vilsbøll, Tina, Knop, Filip Krag, Poulsen, Steen Seier, Jørgensen, Niklas Rye, Holst, Jens Juul, Ørskov, Cathrine & Hartmann, Bolette, 2020, In: Endocrine Connections. 9, 7, p. 747-754

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The combined effect of parathyroid hormone (1-34) and whole-body vibration exercise on physical performance in OSteoporotic women (PaVOS study): A secondary analysis from a randomised controlled trial

    Jepsen, D. B., Masud, T., Holsgaard-Larsen, A., Hansen, S., Jørgensen, Niklas Rye & Ryg, J., 2020, In: BMC Sports Science, Medicine and Rehabilitation. 12, 1, 54.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The effect of 4 months exercise training on systemic biomarkers of cartilage and bone turnover in hip osteoarthritis patients

    Ellegaard, M., Bieler, T., Beyer, N., Kjær, Michael & Jørgensen, Niklas Rye, 2020, In: Translational Sports Medicine. 3, 1, p. 16-25

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The effects of two intervention strategies to reduce the intake of salt and the sodium-to-potassium ratio on cardiovascular risk factors: A 4-month randomised controlled study among healthy families

    Toft, Ulla Marie Nørgaard, Riis, N. L., Lassen, A. D., Trolle, E., Andreasen, A. H., Frederiksen, A. K. S., Jørgensen, Niklas Rye, Munk, J. K. & Bjoernsbo, K. S., 2020, In: Nutrients. 12, 5, 17 p., 1467.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The utility of magnetic resonance imaging lesion combinations in the sacroiliac joints for diagnosing patients with axial spondyloarthritis. A prospective study of 204 participants including post-partum women, patients with disc herniation, cleaning staff, runners and healthy persons

    Seven, S., Østergaard, Mikkel, Morsel-Carlsen, L., Sørensen, I. J., Bonde, B., Thamsborg, G., Lykkegaard, J. J., Hendricks, O., Jørgensen, Niklas Rye & Pedersen, S. J., 2020, In: Rheumatology. 59, 11, p. 3237-3249 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Unaffected bone mineral density in Danish children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jensen, Andreas Kryger, Jørgensen, Niklas Rye, Olsen, B. S., Pociot, Flemming & Johannesen, Jesper, 2020, In: Journal of Bone and Mineral Metabolism. p. 328–337 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Uncarboxylated matrix Gla-protein: A biomarker of vitamin K status and cardiovascular risk

    Jespersen, T., Møllehave, L. T., Thuesen, B. H., Skaaby, T., Rossing, Peter, Toft, Ulla Marie Nørgaard, Jørgensen, Niklas Rye, Corfixen, B. L., Jakobsen, J., Frimodt-Møller, M. & Linneberg, Allan René, 2020, In: Clinical Biochemistry. 83, p. 49-56 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2019
  19. Published

    Fracture-induced changes in biomarkers CTX, PINP, OC, and BAP-a systematic review

    Højsager, F. D., Rand, M. S., Pedersen, S. B., Nissen, N. & Jørgensen, Niklas Rye, Dec 2019, In: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 30, 12, p. 2381-2389 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Magnetic Resonance Imaging of Lesions in the Sacroiliac Joints for Differentiation of Patients With Axial Spondyloarthritis From Control Subjects With or Without Pelvic or Buttock Pain: A Prospective, Cross-Sectional Study of 204 Participants

    Seven, S., Østergaard, Mikkel, Morsel-Carlsen, L., Sørensen, I. J., Bonde, B., Thamsborg, G., Lykkegaard, J. J., Hendricks, O., Jørgensen, Niklas Rye & Pedersen, S. J., Dec 2019, In: Arthritis & Rheumatology. 71, 12, p. 2034-2046 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    An explorative literature review of the multifactorial causes of osteoporosis in epilepsy

    Diemar, S. S., Sejling, A. S., Eiken, P., Andersen, N. B. & Jørgensen, Niklas Rye, Nov 2019, In: Epilepsy and Behavior. 100, Part A, 10 p., 106511.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Assessment of acute bone loading in humans using [18F]NaF PET/MRI

    Haddock, B., Fan, A. P., Uhlrich, S. D., Jørgensen, Niklas Rye, Suetta, Charlotte, Gold, G. E. & Kogan, F., Nov 2019, In: European Journal of Nuclear Medicine and Molecular Imaging. 46, 12, p. 2452-2463 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Algorithm for the Use of Biochemical Markers of Bone Turnover in the Diagnosis, Assessment and Follow-Up of Treatment for Osteoporosis

    Lorentzon, M., Branco, J., Brandi, M. L., Bruyère, O., Chapurlat, R., Cooper, C., Cortet, B., Diez-Perez, A., Ferrari, S., Gasparik, A., Herrmann, M., Jorgensen, N. R., Kanis, J., Kaufman, J-M., Laslop, A., Locquet, M., Matijevic, R., McCloskey, E., Minisola, S., Pikner, R. & 5 others, Reginster, J., Rizzoli, R., Szulc, P., Vlaskovska, M. & Cavalier, E., Oct 2019, In: Advances in Therapy. 36, 10, p. 2811-2824 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of postmenopausal OSteoporosis (PaVOS study): a randomized controlled trial

    Jepsen, D. B., Ryg, J., Hansen, S., Jørgensen, Niklas Rye, Gram, J. & Masud, T., Sep 2019, In: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 30, 9, p. 1827-1836 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Role of the purinergic P2X receptors in osteoclast pathophysiology

    Jørgensen, Niklas Rye, Aug 2019, In: Current Opinion in Pharmacology. 47, p. 97-101 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    An evaluation of total 25-hydroxyvitamin D assay standardization: Where are we today?

    Bjerg, L. N., Halgreen, J. R., Hansen, S. H., Morris, H. A. & Jørgensen, Niklas Rye, Jun 2019, In: Journal of Steroid Biochemistry and Molecular Biology. 190, p. 224-233

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Bone Health in Patients with Type 2 Diabetes Treated by Roux-En-Y Gastric Bypass and the Role of Diabetes Remission

    Madsen, L. R., Espersen, R., Ornstrup, M. J., Jørgensen, Niklas Rye, Langdahl, B. L. & Richelsen, B., Jun 2019, In: Obesity Surgery. 29, 6, p. 1823-1831 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Elevated Bone Remodeling Markers of CTX and P1NP in Addition to Sclerostin in Patients with X-linked Hypophosphatemia: A Cross-Sectional Controlled Study

    Hansen, S., Shanbhogue, V. V., Jørgensen, Niklas Rye & Beck-Nielsen, S. S., Jun 2019, In: Calcified Tissue International. 104, 6, p. 591-598 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Effects of Dapagliflozin on Volume Status When Added to Renin-Angiotensin System Inhibitors

    Eickhoff, M. K., Dekkers, C. C. J., Kramers, B. J., Laverman, G. D., Frimodt-Møller, M., Jørgensen, Niklas Rye, Faber, Jens, Danser, A. H. J., Gansevoort, R. T., Rossing, Peter, Persson, F. & Heerspink, H. J. L., 31 May 2019, In: Journal of Clinical Medicine. 8, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Bone turnover markers are differentially affected by pre-analytical handling

    Christensen, G. L., Halgreen, J. R., Milenkovski, M., Köse, A., Quardon, N. & Jørgensen, Niklas Rye, May 2019, In: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 30, 5, p. 1137-1141 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  31. Published

    Anogenital distance is associated with semen quality but not reproductive hormones in 1106 young men from the general population

    Priskorn, L., Bang, A. K., Nordkap, L., Krause, M., Mendiola, J., Jensen, T. K., Juul, Anders, Skakkebæk, Niels Erik, Swan, S. H. & Jørgensen, Niklas Rye, 1 Jan 2019, In: Human reproduction (Oxford, England). 34, 1, p. 12-24 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Bone mass development in childhood and its association with physical activity and vitamin D levels. The CHAMPS-Study DK

    Rønne, M. S., Heidemann, M., Lylloff, L., Schou, A. J., Tarp, J., Laursen, J. O., Jørgensen, Niklas Rye, Husby, S., Wedderkopp, N. & Mølgaard, Christian, 2019, In: Calcified Tissue International. 104, 1, p. 1-13 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Bone mass development is sensitive to insulin resistance in adolescent boys

    Rønne, M. S., Heidemann, M., Lylloff, L., Schou, A. J., Tarp, J., Bugge, A., Laursen, J. O., Jørgensen, Niklas Rye, Husby, S., Wedderkopp, N. & Mølgaard, Christian, 2019, In: Bone. 122, p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Calcitonin-gene related peptide and disease activity in cluster headache

    Snoer, A., Vollesen, A. L. H., Beske, R. P., Guo, S., Hoffmann, J., Fahrenkrug, J., Jørgensen, Niklas Rye, Martinussen, Torben, Jensen, Rigmor Højland & dlt446, dlt446, 2019, In: Cephalalgia. 39, 5, p. 575-584

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    History of cardiovascular disease and cardiovascular biomarkers are associated with 30-day mortality in patients with hip fracture

    Norring-Agerskov, D., Madsen, C. M., Bathum, L., Pedersen, O. B., Lauritzen, Jes Bruun, Jørgensen, Niklas Rye & Jørgensen, Henrik Løvendahl, 2019, In: Osteoporosis International. 30, p. 1767-1778 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Kinetic [18F]-Fluoride of the Knee in Normal Volunteers

    Haddock, B., Fan, A. P., Jørgensen, Niklas Rye, Suetta, Charlotte, Gold, G. E. & Kogan, F., 2019, In: Clinical Nuclear Medicine. 44, 5, p. 377-385 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Markers of bone turnover are reduced in patients with CF related diabetes; the role of glucose

    Mathiesen, I. H., Hitz, Mette Friberg, Katzenstein, T. L., Oturai, P., Skov, M., Jørgensen, Niklas Rye, Jensen, Peter Østrup, Mikkelsen, C. R., Krogh-Madsen, Rikke, Pressler, T. & Faurholt-Jepsen, D., 2019, In: Journal of Cystic Fibrosis. 18, 3, p. 436-441

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study

    Bryrup, T., Thomsen, C. W., Kern, T., Allin, K. H., Brandslund, I., Jørgensen, Niklas Rye, drb459, drb459, Hansen, Torben, Hansen, T. H., Pedersen, Oluf Borbye & Nielsen, T., 2019, In: Diabetologia. 62, 6, p. 1024-1035

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Multiple Fractures and Impaired Bone Fracture Healing in a Patient with Pycnodysostosis and Hypophosphatasia

    Hepp, N., Frederiksen, A. L., Dunø, M., Jørgensen, Niklas Rye, Langdahl, B. L., Vedtofte, P., Hove, H. B., Hindsø, Klaus & Jensen, Jens-Erik Beck, 2019, In: Calcified Tissue International. 105, p. 681-686 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    O12.4. EFFECTS OF THE GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST EXENATIDE ON BONE STATUS IN OBESE, NON-DIABETIC, ANTIPSYCHOTIC-TREATED SCHIZOPHRENIA SPECTRUM PATIENTS

    Eriksson, R., Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jørgensen, Niklas Rye, Knop, Filip Krag & Ebdrup, Bjørn, 2019, In: Schizophrenia Bulletin. 45, Suppl. 2, p. S198-S199 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  41. Published

    THE DIAGNOSTIC UTILITY OF THE RELATION BETWEEN MRI BONE MARROW EDEMA AND OTHER TYPES OF MRI LESIONS IN THE SACROILIAC JOINTS IN AXIAL SPONDYLOARTHRITIS

    Seven, S., Hededal, P., Østergaard, Mikkel, Morsel-Carlsen, L., Sørensen, I. J., Bonde, B., Thamsborg, G., Lykkegaard, J. J., Hendricks, O., Jørgensen, Niklas Rye & Pedersen, S. J., 2019, In: Annals of the Rheumatic Diseases. 78, Suppl 2, p. 464-466 THU0364.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  42. Published

    The diurnal variation of bone formation is attenuated in adult patients with type 2 diabetes

    Hygum, K., Starup-Linde, J., Harslor, T., Jørgensen, Niklas Rye, Hartmann, Bolette, Holst, Jens Juul & Langdahl, B. L., 2019, In: European Journal of Endocrinology. 181, 3, p. 221-231

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2018
  44. Published

    Glucose-Dependent Insulinotropic Polypeptide (GIP) Inhibits Bone Resorption Independently of Insulin and Glycemia

    Christensen, Mikkel Bring, Lund, A., Calanna, S., Jørgensen, Niklas Rye, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Jan 2018, In: The Journal of clinical endocrinology and metabolism. 103, 1, p. 288-294

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Chronic hyponatremia - Why care? A case report

    Diemar, S. S., Sejling, A., Jørgensen, Niklas Rye & Andersen, N. B., 2018, In: Seizure. 59, p. 123-125

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Comparison of bone turnover markers in peripheral blood and bone marrow aspirate

    Ornstrup, M. J., Kjær, T. N., Harsløf, T., Jørgensen, Niklas Rye, Pedersen, S. B. & Langdahl, B. L., 2018, In: Bone. 116, p. 315-320

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Effects of metformin, rosiglitazone and insulin on bone metabolism in patients with type 2 diabetes

    Stage, T. B., Christensen, M. H., Jørgensen, Niklas Rye, Beck-Nielsen, H., Brøsen, K., Gram, J. & Frost, M., 2018, In: Bone. 112, p. 35-41 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    High on-treatment platelet reactivity in Danish hyper-acute ischaemic stroke patients

    Rath, C. L., Jørgensen, Niklas Rye & Wienecke, Troels, 2018, In: Frontiers in Neurology. 9, AUG, 8 p., 712.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Impact of Conventional Medical Therapy on Bone Mineral Density and Bone Turnover in Adult Patients with X-Linked Hypophosphatemia: A 6-Year Prospective Cohort Study

    Shanbhogue, V. V., Hansen, S., Jørgensen, Niklas Rye & Beck-Nielsen, S. S., 2018, In: Calcified Tissue International. 102, 3, p. 321-328 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Knogletæthedsmåling og biomarkører til monitorering af osteoporosebehandling

    Pedersen, S. B., Rand, M. S., Eiken, P. A. & Jørgensen, Niklas Rye, 2018, In: Ugeskrift for Laeger. 180, 32, 5 p., V12170926.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Melatonin and cortisol in individuals with spinal cord injury

    Thøfner Hultén, V. D., Biering-Sørensen, Fin, Jørgensen, Niklas Rye & Jennum, Poul, 2018, In: Sleep Medicine. 51, p. 92-98

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption

    Bergmann, N. C., Lund, A., Heimburger, S. M., Gasbjerg, Lærke Smidt, Jørgensen, Niklas Rye, Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, S.1, p. S348-S348 717.

    Research output: Contribution to journalConference abstract in journalResearch

  53. Published

    P2X7 receptor regulates osteoclast function and bone loss in a mouse model of osteoporosis

    Wang, N., Agrawal, A., Jørgensen, Niklas Rye & Gartland, A., 2018, In: Scientific Reports. 8, 10 p., 3507.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 985846