Niklas Rye Jørgensen

Niklas Rye Jørgensen

Clinical Professor

Member of:

  • Clinical Biochemistry


  1. 2008
  2. Published

    Variation in the purinergic P2RX(7) receptor gene and schizophrenia

    Hansen, T., Jakobsen, K. D., Fenger, M., Nielsen, J., Krane, K., Fink-Jensen, Anders, Lublin, H., Ullum, H., Timm, S., Wang, August Gabriel, Jørgensen, Niklas Rye & Werge, Thomas, 2008, In: Schizophrenia Research. 104, 1-3, p. 146-52 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2009
  4. Published

    Alpha-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis

    Skals, M., Jørgensen, Niklas Rye, Leipziger, J. & Praetorius, H. A., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 10, p. 4030-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2012
  6. Published

    Nanocoating of titanium implant surfaces with organic molecules. Polysaccharides including glycosaminoglycans

    Gurzawska, K. A., Svava, R., Jørgensen, Niklas Rye & Gotfredsen, Klaus, 2012, In: Journal of Biomedical Nanotechnology. 8, 6, p. 1012-24 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2013
  8. Published

    Association of P2X7 receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, A., Bours, M. J. L., Henriksen, Z., Syberg, S., Petersen, S., Schwarz, Peter, Jørgensen, Niklas Rye, van Helden, S. & Dagnelie, P. C., 2013, In: Osteoporosis International. 24, 4, p. 1235-1246 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Association of P2Y(2) receptor SNPs with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, A., Bours, M. J. L., Henriksen, Z., Syberg, S., Petersen, S., Schwarz, Peter, Jørgensen, Niklas Rye, van Helden, S. & Dagnelie, P. C., 2013, In: Purinergic Signalling. 9, 1, p. 41-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Characterization of pectin nanocoatings at polystyrene and titanium surfaces

    Gurzawska, K. A., Dirscherl, K., Yihua, Y., Chrestensen, I. B., Jørgensen, Bodil, Svava, R., Nielsen, M. W., Jørgensen, Niklas Rye & Gotfredsen, Klaus, 2013, In: Journal of Surface Engineered Materials and Advanced Technology. 3, p. 20-28 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Gastrointestinal Events with Clopidogrel: A Nationwide Population-Based Cohort Study

    Grove, E. L., Würtz, M., Schwarz, Peter, Jørgensen, Niklas Rye & Vestergaard, P., 2013, In: Journal of General Internal Medicine. 28, 2, p. 216-22 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Non-synonymous polymorphisms in the P2RX ( 4 ) are related to bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, A., Bours, M. J., Jørgensen, Niklas Rye, Wiley, J., Gu, B., van Helden, S., van Rhijn, L. & Dagnelie, P. C., 2013, In: Purinergic Signalling. 9, 1, p. 123-30 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Functional polymorphisms in the P2X7 receptor gene are associated with osteoporosis

    Husted, L. B., Harsløf, T., Stenkjær, L., Carstens, M., Jørgensen, Niklas Rye & Langdahl, B. L., Mar 2013, In: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 24, 3, p. 949-59 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Adipose derived mesenchymal stem cells – Their osteogenicity and osteoblast in vitro mineralization on titanium granule carriers

    Dahl, M., Syberg, S., Jørgensen, Niklas Rye & Pinholt, E. M., 13 Nov 2013, In: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 41, 2013, p. 213 -220 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2014
  16. Published

    Non-infectious osteomyelitis of the mandible in a young woman: a case report

    Rasmussen, A. Q., Andersen, U. B., Jørgensen, Niklas Rye & Schwarz, Peter, 2014, In: Journal of Medical Case Reports. 8, p. 1-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Osteoblastic response to pectin nanocoating on titanium surfaces

    Gurzawska, K. A., Svava, R., Yihua, Y., Haugshøj, K. B., Dirscherl, K., Levery, S. B., Chrestensen, I. B., Damager, I., Weiss Nielsen, M., Jørgensen, Bodil, Jørgensen, Niklas Rye & Gotfredsen, Klaus, 2014, In: Materials Science and Engineering C: Materials for Biological Applications. 43, p. 117-125 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Plasma plasminogen activator inhibitor-1 predicts myocardial infarction in HIV-1-infected individuals

    Knudsen, A., Katzenstein, T. L., Benfield, Thomas, Jørgensen, Niklas Rye, Kronborg, Gitte, Gerstoft, Jan, Obel, Niels, Kjær, Andreas & Lebech, Anne-Mette, 2014, In: AIDS. 28, 8, p. 1171-1179 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Recreational football improves bone mineral density and bone turnover marker profile in elderly men

    Helge, Eva Wulff, Rostgaard Andersen, T., Schmidt, J. F., Jørgensen, Niklas Rye, Hornstrup, T., Krustrup, P. & Bangsbo, Jens, 2014, In: Scandinavian Journal of Medicine & Science in Sports. 24, Suppl. 1, p. 98-104 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The P2X7 receptor: a key player in immune-mediated bone loss?

    Kvist, T. M., Schwarz, Peter & Jørgensen, Niklas Rye, 2014, In: Scientific World Journal. 2014, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The structurally effect of surface coated rhamnogalacturonan I on response of the osteoblast-like cell line SaOS-2

    Svava, R., Gurzawska, K., Yihau, Y., Haugshøj, K. B., Dirscherl, K., Levery, S. B., Jørgensen, Niklas Rye, Gotfredsen, Klaus, Damager, I., Ulvskov, Peter & Jørgensen, Bodil, 2014, In: Journal of Biomedical Materials Research. Part A. 102, 6, p. 1961-1971 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published
  23. Published

    Carriers in mesenchymal stem cell osteoblast mineralization-State-of-the-art

    Dahl, M., Jørgensen, Niklas Rye, Hørberg, M. & Pinholt, E. M., Jan 2014, In: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 42, 1, p. 41-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Status of drug development for the prevention and treatment of osteoporosis

    Schwarz, Peter, Jørgensen, Niklas Rye & Abrahamsen, B., Mar 2014, In: Expert Opinion on Drug Discovery. 9, 3, p. 245-253 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Genetic variants in the P2RX7 gene are associated with risk of multiple myeloma

    Vangsted, A. J., Klausen, T. W., Gimsing, P., Abildgaard, N., Andersen, N. F., Gang, A. O., Holmström, M., Gregersen, H., Vogel, U., Schwarz, Peter & Jørgensen, Niklas Rye, Aug 2014, In: European Journal of Haematology. 93, 2, p. 172-174 3 p.

    Research output: Contribution to journalComment/debateResearch

  26. Published

    Bone Geometry, Volumetric Density, Microarchitecture, and Estimated Bone Strength Assessed by HR-pQCT in Klinefelter Syndrome

    Shanbhogue, V. V., Hansen, S., Jørgensen, Niklas Rye, Brixen, K. & Gravholt, C. H., Nov 2014, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 29, 11, p. 2474–2482 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Muscle strength, power and cardiorespiratory fitness are associated with bone mineral density in men aged 31-60 years

    Schwarz, Peter, Jørgensen, Niklas Rye, Nielsen, B., Laursen, A. S., Linneberg, Allan René & Aadahl, Mette, Dec 2014, In: Scandinavian Journal of Public Health. 42, 8, p. 773-779 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2015
  29. Published

    Effects of soccer vs swim training on bone formation in sedentary middle-aged women

    Mohr, M., Helge, Eva Wulff, Petersen, L. F., Lindenskov, A., Weihe, P., Mortensen, Jann, Jørgensen, Niklas Rye & Krustrup, P., 2015, In: European Journal of Applied Physiology. 115, 12, p. 2671-2679 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    G-protein mediated signaling pathways in myogenic responsiveness of mouse mesenteric artery

    Jensen, Lars Jørn, Joseph, P. D., Haanes, Kristian Agmund, Hansen, S. S., Jørgensen, Niklas Rye, Hansen, J. L. & Salomonsson, M., 2015, In: Microcirculation. 22, 7, p. 631 1 p., P119.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  31. Published

    GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women

    Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    No changes in serum tryptase after bariatric surgery

    Skaaby, T., drb459, drb459, Thomsen, S., Knudsen, A. L., Jørgensen, Niklas Rye & Linneberg, Allan René, 2015, In: Annals of Epidemiology. 25, 10, p. 800-1 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The role of P2X receptors in bone biology

    Jørgensen, Niklas Rye, Syberg, S. & Ellegaard, M., 2015, In: Current Medicinal Chemistry. 22, 7, p. 902-14 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Epidemiology of forearm fractures in adults in Denmark: national age- and gender-specific incidence rates, ratio of forearm to hip fractures, and extent of surgical fracture repair in inpatients and outpatients

    Abrahamsen, B., Jørgensen, Niklas Rye & Schwarz, Peter, Jan 2015, In: Osteoporosis international with other metabolic bone diseases. 26, 1, p. 67-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Accelerated tumor progression in mice lacking the ATP receptor P2X7

    Adinolfi, E., Capece, M., Franceschini, A., Falzoni, S., Giuliani, A. L., Rotondo, A., Sarti, A. C., Bonora, M., Syberg, S., Corigliano, D., Pinton, P., Jørgensen, Niklas Rye, Abelli, L., Emionite, L., Raffaghello, L., Pistoia, V. & Di Virgilio, F., 15 Feb 2015, In: Cancer Research. 75, 4, p. 635-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Application of high resolution synchrotron micro-CT radiation in dental implant osseointegration

    Neldam, C. A., Lauridsen, T., Rack, A., Lefolii, T. T., Jørgensen, Niklas Rye, Feidenhans'l, Robert Krarup & Pinholt, E. M., 1 Jun 2015, In: Journal of Cranio-Maxillofacial Surgery. 43, 5, p. 682-687 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The Impact of Nocturnal Hypoglycemia on Sleep in Subjects With Type 2 Diabetes

    Jennum, Poul, Stender-Petersen, K., Rabøl, R., Jørgensen, Niklas Rye, Chu, P. & Madsbad, Sten, Nov 2015, In: Diabetes Care. 38, 11, p. 2151-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Bone Geometry, Volumetric Density, Microarchitecture, and Estimated Bone Strength Assessed by HR-pQCT in Adult Patients With Type 1 Diabetes Mellitus

    Shanbhogue, V. V., Hansen, S., Frost, M., Jørgensen, Niklas Rye, Hermann, A. P., Henriksen, J. E. & Brixen, K., Dec 2015, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30, 12, p. 2188-99 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2016
  40. Published

    New insights on pyrimidine signalling within the arterial vasculature: Different roles for P2Y2 and P2Y6 receptors in large and small coronary arteries of the mouse

    Haanes, K. A., Spray, S., Syberg, S., Jørgensen, Niklas Rye, Robaye, B., Boeynaems, J. & Edvinsson, L., Apr 2016, In: Journal of Molecular and Cellular Cardiology. 93, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Soluble urokinase plasminogen activator receptor (suPAR) is a novel, independent predictive marker of myocardial infarction in HIV-1-infected patients: a nested case-control study

    Rasmussen, L. J. H., Knudsen, A., Katzenstein, T. L., Gerstoft, Jan, Obel, Niels, Jørgensen, Niklas Rye, Kronborg, Gitte, Benfield, Thomas, Kjær, Andreas, Eugen-Olsen, J. & Lebech, Anne-Mette, May 2016, In: HIV Medicine. 17, 5, p. 350-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2017
  43. Published

    Bone structural changes after gastric bypass surgery evaluated by HR-pQCT: a two-year longitudinal study

    Shanbhogue, V. V., Støving, R. K., Frederiksen, K. H., Hanson, S., Brixen, K., Gram, J., Jørgensen, Niklas Rye & Hansen, S., 2017, In: European Journal of Endocrinology. 176, 6, p. 685-693

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Bone turnover is altered in transgenic rats overexpressing the P2Y2 purinergic receptor

    Ellegaard, M., Agca, C., Petersen, S., Agrawal, A., Kruse, L. S., Wang, N., Gartland, A., Jensen, J. B., Jørgensen, Niklas Rye & Agca, Y., 2017, In: Purinergic Signalling. 13, 4, p. 545-557

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Clinical usefulness of bone turnover marker concentrations in osteoporosis

    IFCC-IOF Working Group for Standardisation of Bone Marker Assays (WG-BMA), I. W. G. F. S. O. B. M. A. (., 2017, In: Clinica Chimica Acta. 467, p. 34-41

    Research output: Contribution to journalReviewResearchpeer-review

  46. Published

    Effect of whole-body vibration exercise in preventing falls and fractures: a systematic review and meta-analysis

    Jepsen, D. B., Thomsen, K., Hansen, S., Jørgensen, Niklas Rye, Masud, T. & Ryg, J., 2017, In: B M J Open. 7, 12, 15 p., e018342.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Evidence for the prevention of bone loss in elderly and old early non-metastatic breast cancer patients treated with aromatase inhibitors

    Gunmalm, V., Jørgensen, Niklas Rye, Abrahamsen, B. & Schwarz, Peter, 2017, In: European Geriatric Medicine. 8, 5-6, p. 408-412

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Hyperkalemia is Associated with Increased 30-Day Mortality in Hip Fracture Patients

    Norring-Agerskov, D., Madsen, C. M., Abrahamsen, B., Riis, T., Pedersen, Ole Birger Vesterager, Jørgensen, Niklas Rye, Bathum, L., Lauritzen, Jes Bruun & Jørgensen, H. L., 2017, In: Calcified Tissue International. 101, 1, p. 9-16

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Optimizing combination of vascular endothelial growth factor and mesenchymal stem cells on ectopic bone formation in SCID mice

    Dreyer, C. H., Kjaergaard, K., Ditzel, N., Jørgensen, Niklas Rye, Overgaard, Søren & Ding, M., 2017, In: Journal of Biomedical Materials Research. Part A. 105, 12, p. 3326-3332

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    P2Y12 Receptor Antagonist, Clopidogrel, Does Not Contribute to Risk of Osteoporotic Fractures in Stroke Patients

    Jørgensen, Niklas Rye, Schwarz, Peter, Iversen, Helle Klingenberg & Vestergaard, P., 2017, In: Frontiers in Pharmacology. 8, 8 p., 821.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Reliability of the Biochemical Bone Markers CTX and P1NP during a TNF-Inhibitor Treatment Cycle in Patients with Rheumatoid Arthritis

    Holmsted, K., Jørgensen, Niklas Rye & gjc556, gjc556, 2017, In: Arthritis & Rheumatology. 69, S10, 2 p., 2382.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  52. Published

    P2X7Rs are involved in cell death, growth and cellular signaling in primary human osteoblasts

    Agrawal, A., Henriksen, Z., Syberg, S., Petersen, S., Aslan, D., Solgaard, M., Nissen, N., Larsen, T. K., Schwarz, Peter, Steinberg, T. H. & Jørgensen, Niklas Rye, Feb 2017, In: Bone. 95, p. 91-101 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Synchrotron radiation μCT and histology evaluation of bone-to-implant contact

    Neldam, C. A., Sporring, Jon, Rack, A., Lauridsen, T., Hauge, E. M., Jørgensen, H. L., Jørgensen, Niklas Rye, Feidenhans'l, Robert Krarup & Pinholt, E. M., Sep 2017, In: Journal of Cranio-Maxillofacial Surgery. 45, 9, p. 1448-1457 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    The role of the P2X7 receptor on bone loss in a mouse model of inflammation-mediated osteoporosis

    Kvist, T. M., Syberg, S., Petersen, S., Ding, M., Jørgensen, Niklas Rye & Schwarz, Peter, Dec 2017, In: Bone Reports. 7, p. 145-151 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2018
  56. Published

    Chronic hyponatremia - Why care? A case report

    Diemar, S. S., Sejling, A., Jørgensen, Niklas Rye & Andersen, N. B., 2018, In: Seizure. 59, p. 123-125

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Comparison of bone turnover markers in peripheral blood and bone marrow aspirate

    Ornstrup, M. J., Kjær, T. N., Harsløf, T., Jørgensen, Niklas Rye, Pedersen, S. B. & Langdahl, B. L., 2018, In: Bone. 116, p. 315-320

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Effects of metformin, rosiglitazone and insulin on bone metabolism in patients with type 2 diabetes

    Stage, T. B., Christensen, M. H., Jørgensen, Niklas Rye, Beck-Nielsen, H., Brøsen, K., Gram, J. & Frost, M., 2018, In: Bone. 112, p. 35-41 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    High on-treatment platelet reactivity in Danish hyper-acute ischaemic stroke patients

    Rath, C. L., Jørgensen, Niklas Rye & Wienecke, Troels, 2018, In: Frontiers in Neurology. 9, AUG, 8 p., 712.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Impact of Conventional Medical Therapy on Bone Mineral Density and Bone Turnover in Adult Patients with X-Linked Hypophosphatemia: A 6-Year Prospective Cohort Study

    Shanbhogue, V. V., Hansen, S., Jørgensen, Niklas Rye & Beck-Nielsen, S. S., 2018, In: Calcified Tissue International. 102, 3, p. 321-328 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Knogletæthedsmåling og biomarkører til monitorering af osteoporosebehandling

    Pedersen, S. B., Rand, M. S., Eiken, P. A. & Jørgensen, Niklas Rye, 2018, In: Ugeskrift for Laeger. 180, 32, 5 p., V12170926.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Melatonin and cortisol in individuals with spinal cord injury

    Thøfner Hultén, V. D., Biering-Sørensen, Fin, Jørgensen, Niklas Rye & Jennum, Poul, 2018, In: Sleep Medicine. 51, p. 92-98

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption

    Bergmann, N. C., Lund, A., Heimburger, S. M., Gasbjerg, Lærke Smidt, Jørgensen, Niklas Rye, Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, S.1, p. S348-S348 717.

    Research output: Contribution to journalConference abstract in journalResearch

  64. Published

    P2X7 receptor regulates osteoclast function and bone loss in a mouse model of osteoporosis

    Wang, N., Agrawal, A., Jørgensen, Niklas Rye & Gartland, A., 2018, In: Scientific Reports. 8, 10 p., 3507.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of OSteoporosis (PaVOS)- study protocol for a randomized controlled trial

    Jepsen, D. B., Ryg, J., Jørgensen, Niklas Rye, Hansen, S. & Masud, T., 2018, In: Trials. 19, 9 p., 186.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Glucose-Dependent Insulinotropic Polypeptide (GIP) Inhibits Bone Resorption Independently of Insulin and Glycemia

    Christensen, Mikkel Bring, Lund, A., Calanna, S., Jørgensen, Niklas Rye, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Jan 2018, In: The Journal of clinical endocrinology and metabolism. 103, 1, p. 288-294

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. 2019
  68. Published

    Bone mass development in childhood and its association with physical activity and vitamin D levels. The CHAMPS-Study DK

    Rønne, M. S., Heidemann, M., Lylloff, L., Schou, A. J., Tarp, J., Laursen, J. O., Jørgensen, Niklas Rye, Husby, S., Wedderkopp, N. & Mølgaard, Christian, 2019, In: Calcified Tissue International. 104, 1, p. 1-13 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Bone mass development is sensitive to insulin resistance in adolescent boys

    Rønne, M. S., Heidemann, M., Lylloff, L., Schou, A. J., Tarp, J., Bugge, A., Laursen, J. O., Jørgensen, Niklas Rye, Husby, S., Wedderkopp, N. & Mølgaard, Christian, 2019, In: Bone. 122, p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Calcitonin-gene related peptide and disease activity in cluster headache

    Snoer, A., Vollesen, A. L. H., Beske, R. P., Guo, S., Hoffmann, J., Fahrenkrug, J., Jørgensen, Niklas Rye, Martinussen, Torben, Jensen, Rigmor Højland & dlt446, dlt446, 2019, In: Cephalalgia. 39, 5, p. 575-584

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    History of cardiovascular disease and cardiovascular biomarkers are associated with 30-day mortality in patients with hip fracture

    Norring-Agerskov, D., Madsen, C. M., Bathum, L., Pedersen, O. B., Lauritzen, Jes Bruun, Jørgensen, Niklas Rye & Jørgensen, Henrik Løvendahl, 2019, In: Osteoporosis International. 30, p. 1767-1778 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Kinetic [18F]-Fluoride of the Knee in Normal Volunteers

    Haddock, B., Fan, A. P., Jørgensen, Niklas Rye, Suetta, Charlotte, Gold, G. E. & Kogan, F., 2019, In: Clinical Nuclear Medicine. 44, 5, p. 377-385 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Markers of bone turnover are reduced in patients with CF related diabetes; the role of glucose

    Mathiesen, I. H., Hitz, Mette Friberg, Katzenstein, T. L., Oturai, P., Skov, M., Jørgensen, Niklas Rye, Jensen, Peter Østrup, Mikkelsen, C. R., Krogh-Madsen, Rikke, Pressler, T. & Faurholt-Jepsen, D., 2019, In: Journal of Cystic Fibrosis. 18, 3, p. 436-441

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study

    Bryrup, T., Thomsen, C. W., Kern, T., Allin, K. H., Brandslund, I., Jørgensen, Niklas Rye, drb459, drb459, Hansen, Torben, Hansen, T. H., Pedersen, Oluf Borbye & Nielsen, T., 2019, In: Diabetologia. 62, 6, p. 1024-1035

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Multiple Fractures and Impaired Bone Fracture Healing in a Patient with Pycnodysostosis and Hypophosphatasia

    Hepp, N., Frederiksen, A. L., Dunø, M., Jørgensen, Niklas Rye, Langdahl, B. L., Vedtofte, P., Hove, H. B., Hindsø, Klaus & Jensen, Jens-Erik Beck, 2019, In: Calcified Tissue International. 105, p. 681-686 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    O12.4. EFFECTS OF THE GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST EXENATIDE ON BONE STATUS IN OBESE, NON-DIABETIC, ANTIPSYCHOTIC-TREATED SCHIZOPHRENIA SPECTRUM PATIENTS

    Eriksson, R., Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jørgensen, Niklas Rye, Knop, Filip Krag & Ebdrup, Bjørn, 2019, In: Schizophrenia Bulletin. 45, Suppl. 2, p. S198-S199 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  77. Published

    THE DIAGNOSTIC UTILITY OF THE RELATION BETWEEN MRI BONE MARROW EDEMA AND OTHER TYPES OF MRI LESIONS IN THE SACROILIAC JOINTS IN AXIAL SPONDYLOARTHRITIS

    Seven, S., Hededal, P., Østergaard, Mikkel, Morsel-Carlsen, L., Sørensen, I. J., Bonde, B., Thamsborg, G., Lykkegaard, J. J., Hendricks, O., Jørgensen, Niklas Rye & Pedersen, S. J., 2019, In: Annals of the Rheumatic Diseases. 78, Suppl 2, p. 464-466 THU0364.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  78. Published

    The diurnal variation of bone formation is attenuated in adult patients with type 2 diabetes

    Hygum, K., Starup-Linde, J., Harslor, T., Jørgensen, Niklas Rye, Hartmann, Bolette, Holst, Jens Juul & Langdahl, B. L., 2019, In: European Journal of Endocrinology. 181, 3, p. 221-231

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Anogenital distance is associated with semen quality but not reproductive hormones in 1106 young men from the general population

    Priskorn, L., Bang, A. K., Nordkap, L., Krause, M., Mendiola, J., Jensen, T. K., Juul, Anders, Skakkebæk, Niels Erik, Swan, S. H. & Jørgensen, Niklas Rye, 1 Jan 2019, In: Human reproduction (Oxford, England). 34, 1, p. 12-24 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Bone turnover markers are differentially affected by pre-analytical handling

    Christensen, G. L., Halgreen, J. R., Milenkovski, M., Köse, A., Quardon, N. & Jørgensen, Niklas Rye, May 2019, In: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 30, 5, p. 1137-1141 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  81. Published

    Effects of Dapagliflozin on Volume Status When Added to Renin-Angiotensin System Inhibitors

    Eickhoff, M. K., Dekkers, C. C. J., Kramers, B. J., Laverman, G. D., Frimodt-Møller, M., Jørgensen, Niklas Rye, Faber, Jens, Danser, A. H. J., Gansevoort, R. T., Rossing, Peter, Persson, F. & Heerspink, H. J. L., 31 May 2019, In: Journal of Clinical Medicine. 8, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    An evaluation of total 25-hydroxyvitamin D assay standardization: Where are we today?

    Bjerg, L. N., Halgreen, J. R., Hansen, S. H., Morris, H. A. & Jørgensen, Niklas Rye, Jun 2019, In: Journal of Steroid Biochemistry and Molecular Biology. 190, p. 224-233

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Bone Health in Patients with Type 2 Diabetes Treated by Roux-En-Y Gastric Bypass and the Role of Diabetes Remission

    Madsen, L. R., Espersen, R., Ornstrup, M. J., Jørgensen, Niklas Rye, Langdahl, B. L. & Richelsen, B., Jun 2019, In: Obesity Surgery. 29, 6, p. 1823-1831 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Elevated Bone Remodeling Markers of CTX and P1NP in Addition to Sclerostin in Patients with X-linked Hypophosphatemia: A Cross-Sectional Controlled Study

    Hansen, S., Shanbhogue, V. V., Jørgensen, Niklas Rye & Beck-Nielsen, S. S., Jun 2019, In: Calcified Tissue International. 104, 6, p. 591-598 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Role of the purinergic P2X receptors in osteoclast pathophysiology

    Jørgensen, Niklas Rye, Aug 2019, In: Current Opinion in Pharmacology. 47, p. 97-101 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  86. Published

    The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of postmenopausal OSteoporosis (PaVOS study): a randomized controlled trial

    Jepsen, D. B., Ryg, J., Hansen, S., Jørgensen, Niklas Rye, Gram, J. & Masud, T., Sep 2019, In: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 30, 9, p. 1827-1836 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Algorithm for the Use of Biochemical Markers of Bone Turnover in the Diagnosis, Assessment and Follow-Up of Treatment for Osteoporosis

    Lorentzon, M., Branco, J., Brandi, M. L., Bruyère, O., Chapurlat, R., Cooper, C., Cortet, B., Diez-Perez, A., Ferrari, S., Gasparik, A., Herrmann, M., Jorgensen, N. R., Kanis, J., Kaufman, J-M., Laslop, A., Locquet, M., Matijevic, R., McCloskey, E., Minisola, S., Pikner, R. & 5 others, Reginster, J., Rizzoli, R., Szulc, P., Vlaskovska, M. & Cavalier, E., Oct 2019, In: Advances in Therapy. 36, 10, p. 2811-2824 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    An explorative literature review of the multifactorial causes of osteoporosis in epilepsy

    Diemar, S. S., Sejling, A. S., Eiken, P., Andersen, N. B. & Jørgensen, Niklas Rye, Nov 2019, In: Epilepsy and Behavior. 100, Part A, 10 p., 106511.

    Research output: Contribution to journalReviewResearchpeer-review

  89. Published

    Assessment of acute bone loading in humans using [18F]NaF PET/MRI

    Haddock, B., Fan, A. P., Uhlrich, S. D., Jørgensen, Niklas Rye, Suetta, Charlotte, Gold, G. E. & Kogan, F., Nov 2019, In: European Journal of Nuclear Medicine and Molecular Imaging. 46, 12, p. 2452-2463 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Fracture-induced changes in biomarkers CTX, PINP, OC, and BAP-a systematic review

    Højsager, F. D., Rand, M. S., Pedersen, S. B., Nissen, N. & Jørgensen, Niklas Rye, Dec 2019, In: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 30, 12, p. 2381-2389 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  91. Published

    Magnetic Resonance Imaging of Lesions in the Sacroiliac Joints for Differentiation of Patients With Axial Spondyloarthritis From Control Subjects With or Without Pelvic or Buttock Pain: A Prospective, Cross-Sectional Study of 204 Participants

    Seven, S., Østergaard, Mikkel, Morsel-Carlsen, L., Sørensen, I. J., Bonde, B., Thamsborg, G., Lykkegaard, J. J., Hendricks, O., Jørgensen, Niklas Rye & Pedersen, S. J., Dec 2019, In: Arthritis & Rheumatology. 71, 12, p. 2034-2046 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. 2020
  93. Published

    A review of sleep research in patients with spinal cord injury

    Hultén, V. D. T., Biering-Sørensen, Fin, Jørgensen, Niklas Rye & Jennum, Poul, 2020, In: The Journal of Spinal Cord Medicine. 43, 6, p. 775-796

    Research output: Contribution to journalReviewResearchpeer-review

  94. Published

    Adults with pathogenic MC4R mutations have increased final height and thereby increased bone mass

    Iepsen, E. W., Zhang, J., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Jørgensen, Niklas Rye, Holm, Jens-Christian & Torekov, Signe Sørensen, 2020, In: Journal of Bone and Mineral Metabolism. 38, 1, p. 117-125 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Bone Geometry, Density, and Microarchitecture in the Distal Radius and Tibia in Adults With Marfan Syndrome Assessed by HR-pQCT

    Folkestad, L., Groth, K. A., Shanbhogue, V., Hove, H., Kyhl, K., Østergaard, J. R., Jørgensen, Niklas Rye, Andersen, N. H. & Gravholt, C. H., 2020, In: Journal of Bone and Mineral Research. 35, 12, p. 2335-2344

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Bone resorption is unchanged by liraglutide in type 2 diabetes patients: A randomised controlled trial

    Hygum, K., Harsløf, T., Jørgensen, Niklas Rye, Rungby, Jørgen, Pedersen, S. B. & Langdahl, B. L., 2020, In: Bone. 132, 9 p., 115197.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Bone turnover biomarkers in COPD patients randomized to either a regular or shortened course of corticosteroids: A substudy of the randomized controlled CORTICO-COP trial

    Sivapalan, P., Jørgensen, Niklas Rye, Mathioudakis, A. G., Eklöf, J., Lapperre, T., Ulrik, Charlotte Suppli, Andreassen, H. F., Armbruster, K., Sivapalan, P., Janner, J., Godtfredsen, Nina, Weinreich, U. M., Nielsen, T. L., Seersholm, N., Wilcke, T., Schuetz, P., Klausen, T. W., Marså, K., Vestbo, J. & Jensen , Jens-Ulrik Stæhr , 2020, In: Respiratory research. 21, 263.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Bone turnover markers during the remission phase in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jensen, Andreas Kryger, Jørgensen, Niklas Rye, Olsen, B. S., Svensson, Jannet, Pociot, Flemming & Johannesen, Jesper, 2020, In: Pediatric Diabetes. 21, 2, p. 366-376 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Clopidogrel responder status is uninfluenced by CYP2C19∗2 in Danish patients with stroke

    Rath, C. L., Jørgensen, Niklas Rye & Wienecke, Troels, 2020, In: PLoS ONE. 15, 12 , e0236260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Comparative Studies of the Gut Microbiota in the Offspring of Mothers With and Without Gestational Diabetes

    Crusell, Mie Korslund Wiinblad, Hansen, T. H., Nielsen, T., Allin, K. H., Rühlemann, M. C., Damm, Peter, Vestergaard, H., Rørbye, Christina, Jørgensen, Niklas Rye, Christiansen, O. B., Heinsen, F. A., Franke, A., Hansen, Torben, Lauenborg, J. & Pedersen, Oluf Borbye, 2020, In: Frontiers in Cellular and Infection Microbiology. 10, 14 p., 536282.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Continuous decline in bone mineral density and deterioration of bone microarchitecture 7 years after Roux-en-Y gastric bypass surgery

    Hansen, S., Jørgensen, Niklas Rye, Hermann, A. P. & Støving, R. K., 2020, In: European Journal of Endocrinology. 182, 3, p. 303-311 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Decreased markers of bone turnover in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jørgensen, Niklas Rye, Olsen, B. S., Pociot, Flemming & Johannesen, Jesper, 2020, In: Pediatric Diabetes. 21, 3, p. 505-514

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Differential time responses in inflammatory and oxidative stress markers after a marathon: An observational study

    Larsen, E. L., Poulsen, Henrik Enghusen, Michaelsen, C., Kjær, L. K., Lyngbæk, M., Andersen, Emilie Skytte, Petersen-Bønding, C., Lemoine, C., Gillum, M., Jørgensen, Niklas Rye, Ploug, Thorkil, Vilsbøll, Tina, Knop, Filip Krag & Karstoft, K., 2020, In: Journal of Sports Sciences. 38, 18, p. 2080-2091

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Effect of Metformin vs. Placebo in Combination with Insulin Analogues on Bone Markers P1NP and CTX in Patients with Type 2 Diabetes Mellitus

    Nordklint, A. K., Almdal, Thomas Peter, Vestergaard, P., Lundby-Christensen, L., Jørgensen, Niklas Rye, Boesgaard, T. W., Breum, Leif, Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Krarup, T., Madsbad, Sten, Mathiesen, Elisabeth, Perrild, Hans, Tarnow, L., Thorsteinsson, B., Vestergaard, H., Lund, S. S. & Eiken, P., 2020, In: Calcified Tissue International. 107, 2, p. 160-169 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Effects of carbamazepine, eslicarbazepine, valproic acid and levetiracetam on bone microarchitecture in rats

    Diemar, S. S., Sejling, A. S., Eiken, P., Ellegaard, M., Ding, M., Andersen, N. B. & Jørgensen, Niklas Rye, 2020, In: Pharmacological Reports. 72, 5, p. 1323-1333 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    Estimation of lipemia interference with automated HIL-test on d-dimer ACL TOP 50 series analysis: reveals a higher cut-off than manufacturer's recommendations

    Jensen, A. K., Christensen, G. L., Dalgård, A. & Jørgensen, Niklas Rye, 2020, In: Scandinavian Journal of Clinical & Laboratory Investigation. 80, 2, p. 168-171

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    European Biological Variation Study (EuBIVAS): within- and between-subject biological variation estimates of β-isomerized C-terminal telopeptide of type I collagen (β-CTX), N-terminal propeptide of type I collagen (PINP), osteocalcin, intact fibroblast growth factor 23 and uncarboxylated-unphosphorylated matrix-Gla protein-a cooperation between the EFLM Working Group on Biological Variation and the International Osteoporosis Foundation-International Federation of Clinical Chemistry Committee on Bone Metabolism

    Cavalier, E., Lukas, P., Bottani, M., Aarsand, A. K., Ceriotti, F., Coşkun, A., Díaz-Garzón, J., Fernàndez-Calle, P., Guerra, E., Locatelli, M., Sandberg, S., Carobene, A., European Federation of Clinical Chemistry and Laboratory Medicine Working Group on Biological Variation and IOF-IFCC Committee on Bone Metabolism, E. F. O. C. C. A. L. M. W. G. O. B. V. A. I. C. O. B. M., Åkesson, K., Bhattoa, H. P., Bruyère, O., Jørgensen, Niklas Rye, Makris, K., Ulmer, C. Z. & Vasikaran, S. D., 2020, In: Osteoporosis International. 31, 8, p. 1461-1470

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial

    Uth, J., Fristrup, B., Sørensen, V., Helge, Eva Wulff, Christensen, M. K., Kjærgaard, J. B., Møller, T. K. T., Mohr, M., Helge, Jørn Wulff, Jørgensen, Niklas Rye, Rørth, M., Vadstrup, E. S. & Krustrup, P., 2020, In: Progress in Cardiovascular Diseases. 63, 6, p. 792-799 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Fibroblast growth factor-23 is associated with imaging markers of diabetic cardiomyopathy and anti-diabetic therapeutics

    Sørensen, M. H., Bojer, A. S., Jørgensen, Niklas Rye, Broadbent, D. A., Plein, S., Madsen, Per & Gæde, P., 2020, In: Cardiovascular Diabetology. 19, 1, 158.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published
  111. Published

    Glucose-Dependent Insulinotropic Polypeptide (GIP) Reduces Bone Resorption in Patients With Type 2 Diabetes

    Christensen, Mikkel Bring, Lund, A. B., Jørgensen, Niklas Rye, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Journal of the endocrine society. 4, 9, 9 p., 097.

    Research output: Contribution to journalJournal articleResearchpeer-review

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