Niklas Rye Jørgensen
Clinical Professor
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1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans
Sønderby, I. E., van der Meer, D., Moreau, C., Kaufmann, T., Walters, G. B., Ellegaard, M., Abdellaoui, A., Ames, D., Amunts, K., Andersson, M., Armstrong, N. J., Bernard, M., Blackburn, N. B., Blangero, J., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Bülow, R., Bøen, R., Cahn, W. & 31 others, , 2021, In: Translational Psychiatry. 11, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Multicenter Study to Evaluate Harmonization of Assays for C-Terminal Telopeptides of Type I Collagen (ß-CTX): A Report from the IFCC-IOF Committee for Bone Metabolism (C-BM)
Cavalier, E., Eastell, R., Jørgensen, Niklas Rye, Makris, K., Tournis, S., Vasikaran, S., Kanis, J. A., Cooper, C., Pottel, H., Morris, H. A. & on behalf of the IFCC-IOF Committee for Bone Metabolism (C-BM), O. B. O. T. I. C. F. B. M. (., 2021, In: Calcified Tissue International. 108, p. 785–797Research output: Contribution to journal › Journal article › Research › peer-review
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A Systematic Review of the Circadian Rhythm of Bone Markers in Blood
Diemar, S. S., Dahl, S. S., West, A. S., Simonsen, S. A., Iversen, Helle Klingenberg & Jørgensen, Niklas Rye, 2023, In: Calcified Tissue International. 112, 2, p. 126–147 22 p.Research output: Contribution to journal › Review › Research › peer-review
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A feasibility study of training in a local community aimed upon health promotion with special emphasis on musculoskeletal health effects
Prawiradilaga, R. S., Bendtsen, M., Esrup, S., Jørgensen, Niklas Rye, Yulianto, F. A. & Helge, Eva Wulff, 2023, In: F1000Research. 11, 13 p., 51.Research output: Contribution to journal › Journal article › Research › peer-review
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A review of sleep research in patients with spinal cord injury
Hultén, V. D. T., Biering-Sørensen, Fin, Jørgensen, Niklas Rye & Jennum, Poul, 2020, In: The Journal of Spinal Cord Medicine. 43, 6, p. 775-796Research output: Contribution to journal › Review › Research › peer-review
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Absence of P2Y2 Receptor Does Not Prevent Bone Destruction in a Murine Model of Muscle Paralysis-Induced Bone Loss
Agrawal, A., Ellegaard, M., Haanes, Kristian Agmund, Wang, N., Gartland, A., Ding, M., Praetorius, H. & Jørgensen, Niklas Rye, 2022, In: Frontiers in Endocrinology. 13, 17 p., 850525.Research output: Contribution to journal › Journal article › Research › peer-review
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Accelerated tumor progression in mice lacking the ATP receptor P2X7
Adinolfi, E., Capece, M., Franceschini, A., Falzoni, S., Giuliani, A. L., Rotondo, A., Sarti, A. C., Bonora, M., Syberg, S., Corigliano, D., Pinton, P., Jørgensen, Niklas Rye, Abelli, L., Emionite, L., Raffaghello, L., Pistoia, V. & Di Virgilio, F., 15 Feb 2015, In: Cancer Research. 75, 4, p. 635-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adipose derived mesenchymal stem cells – Their osteogenicity and osteoblast in vitro mineralization on titanium granule carriers
Dahl, M., Syberg, S., Jørgensen, Niklas Rye & Pinholt, E. M., 13 Nov 2013, In: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 41, 2013, p. 213 -220 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Administration of whey protein complexed vitamin D3 to vitamin D3-deficient growing Sprague-Dawley rats
Jakobsen, L. M. A., He, W., Ditzel, N., Danielsen, M., Dalsgaard, T. K., Jørgensen, Niklas Rye, Bollen, Peter & Bertram, H. C., 2022, In: Food and Function. 13, 8, p. 4691-4698Research output: Contribution to journal › Journal article › Research › peer-review
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Adrenal suppression in patients with chronic obstructive pulmonary disease treated with glucocorticoids: Role of specific glucocorticoid receptor polymorphisms
Sivapalan, P., Borresen, S. W., Ekloef, J., Klose, M., Holm, F. S., Feldt-Rasmussen, Ulla, Rossing, M., Jørgensen, Niklas Rye, Marvig, R. L., Saeed, M. I., Wilcke, T., Seersholm, N., Mathioudakis, A. G., Vestbo, J. & Jensen , Jens-Ulrik Stæhr , 4 Feb 2022, In: PLoS ONE. 17, 2, 14 p., 0262898.Research output: Contribution to journal › Journal article › Research › peer-review
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Adults with pathogenic MC4R mutations have increased final height and thereby increased bone mass
Iepsen, E. W., Zhang, J., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Jørgensen, Niklas Rye, Holm, Jens-Christian & Torekov, Signe Sørensen, 2020, In: Journal of Bone and Mineral Metabolism. 38, 1, p. 117-125 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Algorithm for the Use of Biochemical Markers of Bone Turnover in the Diagnosis, Assessment and Follow-Up of Treatment for Osteoporosis
Lorentzon, M., Branco, J., Brandi, M. L., Bruyère, O., Chapurlat, R., Cooper, C., Cortet, B., Diez-Perez, A., Ferrari, S., Gasparik, A., Herrmann, M., Jorgensen, N. R., Kanis, J., Kaufman, J-M., Laslop, A., Locquet, M., Matijevic, R., McCloskey, E., Minisola, S., Pikner, R. & 5 others, , Oct 2019, In: Advances in Therapy. 36, 10, p. 2811-2824 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alpha-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis
Skals, M., Jørgensen, Niklas Rye, Leipziger, J. & Praetorius, H. A., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 10, p. 4030-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amylin analog pramlintide induces migraine-like attacks in patients
Ghanizada, H., Al-Karagholi, M. A., Walker, C. S., Arngrim, N., Rees, T., Petersen, J., Siow, A., Mørch-Rasmussen, M., Tan, S., O'Carroll, S. J., Harris, P., Skovgaard, Lene Theil, Jørgensen, Niklas Rye, Brimble, M., Waite, J. S., Rea, B. J., Sowers, L. P., Russo, A. F., Hay, D. L. & dlt446, dlt446, 2021, In: Annals of Neurology. 89, 6, p. 1157-1171 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An evaluation of total 25-hydroxyvitamin D assay standardization: Where are we today?
Bjerg, L. N., Halgreen, J. R., Hansen, S. H., Morris, H. A. & Jørgensen, Niklas Rye, Jun 2019, In: Journal of Steroid Biochemistry and Molecular Biology. 190, p. 224-233Research output: Contribution to journal › Journal article › Research › peer-review
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An explorative literature review of the multifactorial causes of osteoporosis in epilepsy
Diemar, S. S., Sejling, A. S., Eiken, P., Andersen, N. B. & Jørgensen, Niklas Rye, Nov 2019, In: Epilepsy and Behavior. 100, Part A, 10 p., 106511.Research output: Contribution to journal › Review › Research › peer-review
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Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood
Bhattoa, H. P., Cavalier, E., Eastell, R., Heijboer, A. C., Jørgensen, Niklas Rye, Makris, K., Ulmer, C. Z., Kanis, J. A., Cooper, C., Silverman, S. L. & Vasikaran, S. D., 2021, In: Clinica Chimica Acta. 515, p. 16-20 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anogenital distance is associated with semen quality but not reproductive hormones in 1106 young men from the general population
Priskorn, L., Bang, A. K., Nordkap, L., Krause, M., Mendiola, J., Jensen, T. K., Juul, Anders, Skakkebæk, Niels Erik, Swan, S. H. & Jørgensen, Niklas Rye, 1 Jan 2019, In: Human reproduction (Oxford, England). 34, 1, p. 12-24 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of high resolution synchrotron micro-CT radiation in dental implant osseointegration
Neldam, C. A., Lauridsen, T., Rack, A., Lefolii, T. T., Jørgensen, Niklas Rye, Feidenhans'l, Robert Krarup & Pinholt, E. M., 1 Jun 2015, In: Journal of Cranio-Maxillofacial Surgery. 43, 5, p. 682-687 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of acute bone loading in humans using [18F]NaF PET/MRI
Haddock, B., Fan, A. P., Uhlrich, S. D., Jørgensen, Niklas Rye, Suetta, Charlotte, Gold, G. E. & Kogan, F., Nov 2019, In: European Journal of Nuclear Medicine and Molecular Imaging. 46, 12, p. 2452-2463 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of P2X7 receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients
Wesselius, A., Bours, M. J. L., Henriksen, Z., Syberg, S., Petersen, S., Schwarz, Peter, Jørgensen, Niklas Rye, van Helden, S. & Dagnelie, P. C., 2013, In: Osteoporosis International. 24, 4, p. 1235-1246 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of P2Y(2) receptor SNPs with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients
Wesselius, A., Bours, M. J. L., Henriksen, Z., Syberg, S., Petersen, S., Schwarz, Peter, Jørgensen, Niklas Rye, van Helden, S. & Dagnelie, P. C., 2013, In: Purinergic Signalling. 9, 1, p. 41-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Associations between inflammatory markers, body composition, and physical function: the Copenhagen Sarcopenia Study
Kamper, R. S., Alcazar, J., Andersen, L. L., Haddock, B., Jørgensen, Niklas Rye, Hovind, P. & Suetta, Charlotte, 2021, In: Journal of Cachexia, Sarcopenia and Muscle. 12, 6, p. 1641-1652Research output: Contribution to journal › Journal article › Research › peer-review
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Associations between the cortisol awakening response and patient-evaluated stress and mood instability in patients with bipolar disorder: an exploratory study
Faurholt-Jepsen, M., Frøkjær, Vibe Gedsø, Nasser, A., Jørgensen, Niklas Rye, Kessing, Lars Vedel & Vinberg, Maj, Dec 2021, In: International Journal of Bipolar Disorders. 9, 1, 10 p., 8.Research output: Contribution to journal › Journal article › Research › peer-review
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Automated Interlaboratory Comparison of Therapeutic Drug Monitoring Data and Its Use for Evaluation of Published Therapeutic Reference Ranges
Larsen, J. B., Hoffmann-Lücke, E., Aaslo, P. H., Jørgensen, Niklas Rye & Greibe, E., 2023, In: Pharmaceutics. 15, 2, 19 p., 673.Research output: Contribution to journal › Journal article › Research › peer-review
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Baseline bone turnover marker levels can predict change in bone mineral density during antiresorptive treatment in osteoporotic patients: the Copenhagen bone turnover marker study
Bønløkke, S. E., Rand, M. S., Haddock, B., Arup, S., Smith, C. D., Jensen, Jens-Erik Beck, Schwarz, Peter, Hovind, P., Oturai, P. S., Jensen, Lars Thorbjørn, Møller, Søren, Eiken, P., Rubin, K. H., Hitz, Mette Friberg, Abrahamsen, B. & Jørgensen, Niklas Rye, 2022, In: Osteoporosis International. 33, p. 2155–2164Research output: Contribution to journal › Journal article › Research › peer-review
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Biochemical and clinical manifestations in adults with hypophosphatasia: a national cross-sectional study
Hepp, N., Frederiksen, A. L., Duno, M., Jørgensen, Niklas Rye & Jensen, Jens-Erik Beck, 2022, In: Osteoporosis International. 33, p. 2595–2605 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biochemical, clinical and genetic characteristics in adults with persistent hypophosphatasaemia; Data from an endocrinological outpatient clinic in Denmark
Hepp, N., Frederiksen, A. L., Duno, M., Præst Holm, J., Jørgensen, Niklas Rye & Jensen, Jens-Erik Beck, 2021, In: Bone Reports. 15, 101101.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone Geometry, Density, and Microarchitecture in the Distal Radius and Tibia in Adults With Marfan Syndrome Assessed by HR-pQCT
Folkestad, L., Groth, K. A., Shanbhogue, V., Hove, H., Kyhl, K., Østergaard, J. R., Jørgensen, Niklas Rye, Andersen, N. H. & Gravholt, C. H., 2020, In: Journal of Bone and Mineral Research. 35, 12, p. 2335-2344Research output: Contribution to journal › Journal article › Research › peer-review
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Bone Geometry, Volumetric Density, Microarchitecture, and Estimated Bone Strength Assessed by HR-pQCT in Adult Patients With Type 1 Diabetes Mellitus
Shanbhogue, V. V., Hansen, S., Frost, M., Jørgensen, Niklas Rye, Hermann, A. P., Henriksen, J. E. & Brixen, K., Dec 2015, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30, 12, p. 2188-99 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone Geometry, Volumetric Density, Microarchitecture, and Estimated Bone Strength Assessed by HR-pQCT in Klinefelter Syndrome
Shanbhogue, V. V., Hansen, S., Jørgensen, Niklas Rye, Brixen, K. & Gravholt, C. H., Nov 2014, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 29, 11, p. 2474–2482 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone Health in Patients with Type 2 Diabetes Treated by Roux-En-Y Gastric Bypass and the Role of Diabetes Remission
Madsen, L. R., Espersen, R., Ornstrup, M. J., Jørgensen, Niklas Rye, Langdahl, B. L. & Richelsen, B., Jun 2019, In: Obesity Surgery. 29, 6, p. 1823-1831 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone Involvement in Patients with Spondyloarthropathies
Lems, W., Miceli-Richard, C., Haschka, J., Giusti, A., Chistensen, G. L., Kocijan, R., Rosine, N., Jørgensen, Niklas Rye, Bianchi, G. & Roux, C., 2022, In: Calcified Tissue International. 110, 4, p. 393-420 28 p.Research output: Contribution to journal › Review › Research › peer-review
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Bone mass development in childhood and its association with physical activity and vitamin D levels. The CHAMPS-Study DK
Rønne, M. S., Heidemann, M., Lylloff, L., Schou, A. J., Tarp, J., Laursen, J. O., Jørgensen, Niklas Rye, Husby, S., Wedderkopp, N. & Mølgaard, Christian, 2019, In: Calcified Tissue International. 104, 1, p. 1-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone mass development is sensitive to insulin resistance in adolescent boys
Rønne, M. S., Heidemann, M., Lylloff, L., Schou, A. J., Tarp, J., Bugge, A., Laursen, J. O., Jørgensen, Niklas Rye, Husby, S., Wedderkopp, N. & Mølgaard, Christian, 2019, In: Bone. 122, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone phenotype of P2X4 receptor knockout mice: implication of a P2X7 receptor mutation?
Ellegaard, M., Hegner, T., Ding, M., Ulmann, L. & Jørgensen, Niklas Rye, 2021, In: Purinergic Signalling. 17, p. 241–246Research output: Contribution to journal › Journal article › Research › peer-review
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Bone resorption is unchanged by liraglutide in type 2 diabetes patients: A randomised controlled trial
Hygum, K., Harsløf, T., Jørgensen, Niklas Rye, Rungby, Jørgen, Pedersen, S. B. & Langdahl, B. L., 2020, In: Bone. 132, 9 p., 115197.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone structural changes after gastric bypass surgery evaluated by HR-pQCT: a two-year longitudinal study
Shanbhogue, V. V., Støving, R. K., Frederiksen, K. H., Hanson, S., Brixen, K., Gram, J., Jørgensen, Niklas Rye & Hansen, S., 2017, In: European Journal of Endocrinology. 176, 6, p. 685-693Research output: Contribution to journal › Journal article › Research › peer-review
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Bone turnover biomarkers in COPD patients randomized to either a regular or shortened course of corticosteroids: A substudy of the randomized controlled CORTICO-COP trial
Sivapalan, P., Jørgensen, Niklas Rye, Mathioudakis, A. G., Eklöf, J., Lapperre, T., Ulrik, Charlotte Suppli, Andreassen, H. F., Armbruster, K., Sivapalan, P., Janner, J., Godtfredsen, Nina, Weinreich, U. M., Nielsen, T. L., Seersholm, N., Wilcke, T., Schuetz, P., Klausen, T. W., Marså, K., Vestbo, J. & Jensen , Jens-Ulrik Stæhr , 2020, In: Respiratory research. 21, 263.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone turnover is altered in transgenic rats overexpressing the P2Y2 purinergic receptor
Ellegaard, M., Agca, C., Petersen, S., Agrawal, A., Kruse, L. S., Wang, N., Gartland, A., Jensen, J. B., Jørgensen, Niklas Rye & Agca, Y., 2017, In: Purinergic Signalling. 13, 4, p. 545-557Research output: Contribution to journal › Journal article › Research › peer-review
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Bone turnover markers are differentially affected by pre-analytical handling
Christensen, G. L., Halgreen, J. R., Milenkovski, M., Köse, A., Quardon, N. & Jørgensen, Niklas Rye, May 2019, In: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 30, 5, p. 1137-1141 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Bone turnover markers during the remission phase in children and adolescents with type 1 diabetes
Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jensen, Andreas Kryger, Jørgensen, Niklas Rye, Olsen, B. S., Svensson, Jannet, Pociot, Flemming & Johannesen, Jesper, 2020, In: Pediatric Diabetes. 21, 2, p. 366-376 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone-microarchitecture and bone-strength in a sample of adults with hypophosphatasia and a matched reference population assessed by HR-pQCT and impact microindentation
Hepp, N., Folkestad, L., Møllebæk, S., Frederiksen, A. L., Duno, M., Jørgensen, Niklas Rye, Hermann, A. P. & Jensen, Jens-Erik Beck, 2022, In: Bone. 160, 116420.Research output: Contribution to journal › Journal article › Research › peer-review
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Calcitonin-gene related peptide and disease activity in cluster headache
Snoer, A., Vollesen, A. L. H., Beske, R. P., Guo, S., Hoffmann, J., Fahrenkrug, J., Jørgensen, Niklas Rye, Martinussen, Torben, Jensen, Rigmor Højland & dlt446, dlt446, 2019, In: Cephalalgia. 39, 5, p. 575-584Research output: Contribution to journal › Journal article › Research › peer-review
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Carriers in mesenchymal stem cell osteoblast mineralization-State-of-the-art
Dahl, M., Jørgensen, Niklas Rye, Hørberg, M. & Pinholt, E. M., Jan 2014, In: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 42, 1, p. 41-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Changes in RANKL and TRAcP 5b after discontinuation of denosumab suggest RANKL mediated formation of osteoclasts results in the increased bone resorption
Solling, A. S., Harslof, T., Jørgensen, Niklas Rye & Langdahl, B., 2023, In: Osteoporosis International. 34, p. 599–605 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of pectin nanocoatings at polystyrene and titanium surfaces
Gurzawska, K. A., Dirscherl, K., Yihua, Y., Chrestensen, I. B., Jørgensen, Bodil, Svava, R., Nielsen, M. W., Jørgensen, Niklas Rye & Gotfredsen, Klaus, 2013, In: Journal of Surface Engineered Materials and Advanced Technology. 3, p. 20-28 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic hyponatremia - Why care? A case report
Diemar, S. S., Sejling, A., Jørgensen, Niklas Rye & Andersen, N. B., 2018, In: Seizure. 59, p. 123-125Research output: Contribution to journal › Journal article › Research › peer-review
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Circadian rhythm of markers of bone turnover in patients with chronic kidney disease
Hansen, Ditte, Bressendorff, I., Nordholm, A., Jacobsen, A. A., Klausen, T. W. & Jørgensen, Niklas Rye, 2022, In: Bone Reports. 16, 7 p., 101593.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical usefulness of bone turnover marker concentrations in osteoporosis
IFCC-IOF Working Group for Standardisation of Bone Marker Assays (WG-BMA), I. W. G. F. S. O. B. M. A. (., 2017, In: Clinica Chimica Acta. 467, p. 34-41Research output: Contribution to journal › Review › Research › peer-review
ID: 985846
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Characterization of pectin nanocoatings at polystyrene and titanium surfaces
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Kinetic [18F]-Fluoride of the Knee in Normal Volunteers
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The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of postmenopausal OSteoporosis (PaVOS study): a randomized controlled trial
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