Julien Ochala

Julien Ochala

Associate Professor - Promotion Programme

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    ORCID: 0000-0002-6358-2920

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    1. Published

      NEB mutations disrupt the super-relaxed state of myosin and remodel the muscle metabolic proteome in nemaline myopathy

      Ranu, N., Laitila, J., Dugdale, H. F., Mariano, J., Kolb, J. S., Wallgren-Pettersson, C., Witting, N., Vissing, J., Vilchez, J. J., Fiorillo, C., Zanoteli, E., Auranen, M., Jokela, M., Tasca, G., Claeys, K. G., Voermans, N. C., Palmio, J., Huovinen, S., Moggio, M., Beck, T. N. & 3 others, Kontrogianni-Konstantopoulos, A., Granzier, H. & Ochala, Julien, 2022, In: Acta Neuropathologica Communications. 10, 185.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      A Laing distal myopathy-associated proline substitution in the β-myosin rod perturbs myosin cross-bridging activity

      Buvoli, M., Wilson, G. C., Buvoli, A., Gugel, J. F., Hau, A., Bönnemann, C. G., Paradas, C., Ryba, D. M., Woulfe, K. C., Walker, L. A., Buvoli, T., Ochala, Julien & Leinwand, L. A., 2024, In: The Journal of Clinical Investigation. 134, 9, 16 p., :e172599.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      A myopathy-linked tropomyosin mutation severely alters thin filament conformational changes during activation

      Ochala, Julien, Iwamoto, H., Larsson, L. & Yagi, N., 25 May 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 21, p. 9807-12 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      A myopathy-related actin mutation increases contractile function

      Lindqvist, J., Pénisson-Besnier, I., Iwamoto, H., Li, M., Yagi, N. & Ochala, Julien, May 2012, In: Acta Neuropathologica. 123, 5, p. 739-746 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      A rational approach to selective targeting of skeletal myosin

      Katarina Antonovic, A., Ochala, Julien & Fornili, A., 2023, In: Biophysical Journal. 122, 3S1, p. 117a

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Aberrant post-translational modifications compromise human myosin motor function in old age

      Li, M., Ogilvie, H., Ochala, Julien, Artemenko, K., Iwamoto, H., Yagi, N., Bergquist, J. & Larsson, L., Apr 2015, In: Aging Cell. 14, 2, p. 228-35 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Abnormal myosin post-translational modifications and ATP turnover time associated with human congenital myopathy-related RYR1 mutations

      Sonne, A., Antonovic, A. K., Thomsen, Elise Julie Melhedegaard, Akter, F., Andersen, J. L., Jungbluth, H., Witting, N., Vissing, John, Zanoteli, E., Fornili, A. & Ochala, Julien, 2023, In: Acta Physiologica. 239, 2, 14 p., e14035.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity

      Crombie, E. M., Kim, S., Adamson, S., Dong, H., Lu, T. C., Wu, Y., Wu, Y., Levy, Y., Stimple, N., Lam, W. M. R., Hey, H. W. D., Withers, D. J., Hsu, A. L., Bay, B. H., Ochala, Julien & Tsai, S. Y., 2023, In: Journal of Cachexia, Sarcopenia and Muscle. 14, p. 198–213

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Binding pocket dynamics along the recovery stroke of human β-cardiac myosin

      Akter, F., Ochala, Julien & Fornili, A., 2023, In: PLOS Computational Biology. 19, 5, 14 p., e1011099.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Ca2+ sensitizers: An emerging class of agents for counterbalancing weakness in skeletal muscle diseases?

      Ochala, Julien, Feb 2010, In: Neuromuscular Disorders. 20, 2, p. 98-101 4 p.

      Research output: Contribution to journal › Review › Research › peer-review

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