Andres Lopez-Contreras

Andres Lopez-Contreras

Affiliate Associate Professor, Affiliated Associate Professor

Member of:


  1. 2024
  2. Published

    PICH deficiency limits the progression of MYC-induced B-cell lymphoma

    Castejón-Griñán, M., Albers, E., Simón-Carrasco, L., Aguilera, P., Sbroggio, M., Pladevall Morera, David, Ingham, Andreas, Lim, Ernest Wee Kiat, Guillen-Benitez, A., Pietrini, E., Lisby, Michael, Hickson, Ian David & Lopez-Contreras, Andres, 2024, In: Blood Cancer Journal. 14, 1, 15 p., 16.

    Research output: Contribution to journalJournal articlepeer-review

  3. 2022
  4. Published

    ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors

    Pladevall Morera, David, Castejón-Griñán, M., Aguilera, P., Gaardahl, K., Ingham, Andreas, Brosnan-Cashman, J. A., Meeker, A. K. & Lopez-Contreras, Andres, 2022, In: Cancers. 14, 7, 1790.

    Research output: Contribution to journalJournal articlepeer-review

  5. 2021
  6. Published

    Genetic insights into biological mechanisms governing human ovarian ageing

    Ruth, K. S., Day, F. R., Hussain, J., Martinez-Marchal, A., Aiken, C. E., Azad, A., Thompson, D. J., Knoblochova, L., Abe, H., Tarry-Adkins, J. L., Gonzalez, J. M., Fontanillas, P., Claringbould, A., Bakker, O. B., Sulem, P., Walters, R. G., Terao, C., Turon, S., Horikoshi, M., Lin, K. & 36 others, Onland-Moret, N. C., Sankar, A., Hertz, Emil Peter Thrane, Timshel, P. N., Shukla, V., Borup, R., Olsen, K. W., Aguilera, P., Ferrer-Roda, M., Huang, Y., Stankovic, S., Timmers, P. R. H. J., Ahearn, T. U., Alizadeh, B. Z., Naderi, E., Andrulis, I. L., Arnold, A. M., Aronson, K. J., Augustinsson, A., Bojesen, Stig Egil, Hoffding, M. K., Shrikhande, A., Pers, Tune H, Grøndahl, M. L., tcg964, tcg964, Lopez-Contreras, Andres, Daniel, J. A., Hoffmann, Eva, Biobank-based Integrative Omics St, B. I. O. S., eQTLGen Consortium, E. C., BioBank Japan Project, B. J. P., China Kadoorie Biobank Collaborati, C. K. B. C., kConFab Investigators, K. I., LifeLines Cohort Study, L. C. S., InterAct Consortium, I. C. & 23 Me Res Team, 2. M. R. T., 2021, In: Nature. 596, p. 393-397

    Research output: Contribution to journalJournal articlepeer-review

  7. 2020
  8. Published

    ATR expands embryonic stem cell fate potential in response to replication stress

    Atashpaz, S., Samadi Shams, S., Martin Gonzalez, Javier, Sebestyén, E., Arghavanifard, N., Gnocchi, A., Albers, E., Minardi, S., Faga, G., Soffientini, P., Allievi, E., Cancila, V., Bachi, A., Fernández-Capetillo, Ó., Tripodo, C., Ferrari, F., Lopez-Contreras, Andres & Costanzo, V., 2020, In: eLife. 9, e54756.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Supraphysiological protection from replication stress does not extend mammalian lifespan

    Albers, E., Avram, Alexandra Ioana, Sbroggio, M., Fernandez-Capetillo, O. & Lopez-Contreras, Andres, 2020, In: Aging. 12, 7, p. 5612-5624 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. 2019
  11. Published

    TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress

    Lafarga, V., Sung, H., Haneke, K., Roessig, L., Pauleau, A., Bruer, M., Rodriguez-Acebes, S., Lopez-Contreras, Andres, Gruss, O. J., Erhardt, S., Mendez, J., Fernandez-Capetillo, O. & Stoecklin, G., Jan 2019, In: EMBO Reports. 20, 1, e46224.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability

    Pladevall Morera, David, Munk, S., Ingham, Andreas, Garribba, L., Albers, E., Liu, Ying, Olsen, Jesper Velgaard & Lopez-Contreras, Andres, 2019, In: Nucleic Acids Research. 47, 15, p. 8004-8018 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. 2018
  14. The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase

    Lambertos, A., Ramos-Molina, B., Cerezo, D., Lopez-Contreras, Andres & Peñafiel, R., Mar 2018, In: Biochimica et Biophysica Acta - General Subjects. 1862, 3, p. 365-376 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality

    Albers, E., Sbroggiò, M., Pladevall Morera, David, Bizard, A. H., Avram, Alexandra Ioana, Gonzalez, P., Martin Gonzalez, Javier, Hickson, Ian David & Lopez-Contreras, Andres, 2018, In: Cell Reports. 24, 12, p. 3274-3284 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motility

    Lambertos, A., Ramos-Molina, B., Lopez-Contreras, Andres, Cremades, A. & Peñafiel, R., 2018, In: PLoS ONE. 13, 12, 22 p., e0209202.

    Research output: Contribution to journalJournal articlepeer-review

  17. 2017
  18. Published

    A simple DNA recombination screening method by RT-PCR as an alternative to Southern blot

    Albers, E., Sbroggiò, M., Martin Gonzalez, Javier, Avram, Alexandra Ioana, Munk, S. & Lopez-Contreras, Andres, Jun 2017, In: Transgenic Research. 26, 3, p. 429-434 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress

    Munk, S., Sigurðsson, J. O., Xiao, Z., Batth, Tanveer Singh, Franciosa, Giulia, von Stechow, L., Lopez-Contreras, Andres, Vertegaal, A. C. O. & Olsen, Jesper Velgaard, 2017, In: Cell Reports. 21, 2, p. 546-558 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. 2016
  21. Published

    Interventions for age-related diseases: Shifting the paradigm

    Figueira, I., Fernandes, A., Mladenovic Djordjevic, A., Lopez-Contreras, Andres, Henriques, C. M., Selman, C., Ferreiro, E., Gonos, E. S., Trejo, J. L., Misra, J., Rasmussen, Lene Juel, Xapelli, S., Ellam, T. & Bellantuono, I., Dec 2016, In: Mechanisms of Ageing and Development. 160, p. 69-92 24 p.

    Research output: Contribution to journalReviewpeer-review

  22. Published

    DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

    Herrtwich, L., Nanda, I., Evangelou, K., Nikolova, T., Horn, V., Sagar, Erny, D., Stefanowski, J., Rogell, L., Klein, C., Gharun, K., Follo, M., Seidl, M., Kremer, B., Muenke, N., Senges, J., Fliegauf, M., Aschman, T., Pfeifer, D., Sarrazin, S. & 18 others, Sieweke, M. H., Wagner, D., Dierks, C., Haaf, T., Ness, T., Zaiss, M. M., Voll, R. E., Deshmukh, S. D., Prinz, M., Goldmann, T., Hoelscher, C., Hauser, A. E., Lopez-Contreras, Andres, Gruen, D., Gorgoulis, V., Diefenbach, A., Henneke, P. & Triantafyllopoulou, A., 17 Nov 2016, In: Cell. 167, 5, p. 1264–1280.e18

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Efficacy of ATR inhibitors as single agents in Ewing sarcoma

    Nieto-Soler, M., Morgado-Palacin, I., Lafarga, V., Lecona, E., Murga, M., Callen, E., Azorin, D., Alonso, J., Lopez-Contreras, Andres, Nussenzweig, A. & Fernandez-Capetillo, O., 26 Aug 2016, In: OncoTarget. 7, 37, p. 58759-58767

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    USP7 is a SUMO deubiquitinase essential for DNA replication

    Lecona, E., Rodriguez-Acebes, S., Specks, J., Lopez-Contreras, Andres, Ruppen, I., Murga, M., Muñoz, J., Mendez, J. & Fernandez-Capetillo, O., 23 Apr 2016, In: Nature Structural and Molecular Biology. 23, 4, p. 270-277 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. 2015
  26. Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality

    Alvarez, S., Díaz, M., Flach, J., Rodriguez-Acebes, S., Lopez-Contreras, Andres, Martínez, D., Cañamero, M., Fernández-Capetillo, O., Isern, J., Passegué, E. & Méndez, J., 12 Oct 2015, In: Nature Communications. 6, p. 8548

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development

    Specks, J., Lecona, E., Lopez-Contreras, Andres & Fernandez-Capetillo, O., Sep 2015, In: Molecular and Cellular Biology. 35, 17, p. 2910-2917 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells

    Ruiz, S., Lopez-Contreras, Andres, Gabut, M., Marion, R. M., Gutierrez-Martinez, P., Bua, S., Ramirez, O., Olalde, I., Rodrigo-Perez, S., Li, H., Marques-Bonet, T., Serrano, M., Blasco, M. A., Batada, N. N. & Fernandez-Capetillo, O., 21 Aug 2015, In: Nature Communications. 6, p. 8036

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice

    Lopez-Contreras, Andres, Specks, J., Barlow, J. H., Ambrogio, C., Desler, Claus, Vikingsson, S., Rodrigo-Perez, S., Green, H., Rasmussen, Lene Juel, Murga, M., Nussenzweig, A. & Fernandez-Capetillo, O., 1 Apr 2015, In: Genes & Development. 29, 7, p. 690-5 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells

    Ramos-Molina, B., Lopez-Contreras, Andres, Lambertos, A., Dardonville, C., Cremades, A. & Peñafiel, R., 2015, In: Amino Acids. 47, 5, p. 1025-34 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. Modeling the study of DNA damage responses in mice

    Specks, J., Nieto-Soler, M., Lopez-Contreras, Andres & Fernandez-Capetillo, O., 2015, »Mouse Models of Cancer : Methods and Protocols. Eferl, R. & Casanova, E. (eds.). New York: Springer Science+Business Media, Vol. 1267. p. 413-37 25 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  32. PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors

    Farrés, J., Llacuna, L., Martin-Caballero, J., Martínez, C., Lozano, J. J., Ampurdanés, C., Lopez-Contreras, Andres, Florensa, L., Navarro, J., Ottina, E., Dantzer, F., Schreiber, V., Villunger, A., Fernández-Capetillo, O. & Yélamos, J., 2015, In: Cell Death and Differentiation. 22, p. 1144-157 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. 2014
  34. A synthetic lethal interaction between APC/C and topoisomerase poisons uncovered by proteomic screens

    Eguren, M., Álvarez-Fernández, M., García, F., Lopez-Contreras, Andres, Fujimitsu, K., Yaguchi, H., Luque-García, J. L., Fernández-Capetillo, O., Muñoz, J., Yamano, H. & Malumbres, M., 27 Feb 2014, In: Cell Reports. 6, 4, p. 670-83 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Fos-dependent induction of Chk1 protects osteoblasts from replication stress

    Schulze, J., Lopez-Contreras, Andres, Uluçkan, Ö., Graña-Castro, O., Fernandez-Capetillo, O. & Wagner, E. F., 2014, In: Cell Cycle. 13, 12, p. 1980-6 7 p.

    Research output: Contribution to journalJournal articlepeer-review

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