The IFAST project – University of Copenhagen

The IFAST project 

This study will investigate the effects of short-term intermittent fasting on insulin resistance (IFAST). During intermittent fasting, periods of fasting are alternated with periods of eating. Recent findings suggest that it has beneficial effects on glucose homeostasis even in the absence of net weight loss. Here, a clinical study will explore the effects of intermittent fasting on glucose metabolism in patients with type 2 diabetes. Possible mechanisms will be explored. Preliminary data shows a high compliance to the intervention, a decrease in central obesity after the intervention and change in mitochondrial ADP sensitivity in skeletal muscle. The impact of the intervention on glucose homeostasis is not yet known.