The Ubberup project – University of Copenhagen

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Healthy Aging UK > Research > Cross-Theme Projects > The Ubberup project

The Ubberup project

The world-wide increasing prevalence of obesity is a combined effect of low compliance with daily goals for physical activity and high daily caloric intake, such that average daily calories consumed exceeds average daily calories burned.

Weight loss can be achieved by a change of life style, which includes daily participation in physical activity: this kind of life-style change often requires participation in an intense, prolonged course in life-style modification, under supervision. Many who enroll in such a course see immediate positive impact, including weight loss; however, the majority of participants fail to remain committed over the long term to a change in life style, rapidly regaining lost weight after the supervised intervention ends.

This project will characterize the physiological factors that determine/influence an individual’s capacity to maintain weight loss and to change lifestyle after the end of a prolonged lifestyle intervention. The study has a cross-sectional (n=80) component and a longitudinal (n=80) component, and will be conducted at Center for Healthy Aging and Ubberup College (only in Danish).

Endpoints monitored during the study include body composition, aerobic fitness, capacity for fat oxidation, mitochondrial function, inflammation, glucose metabolism etc. The societal impact of obesity is huge and reaching unprecedented levels. We strive to identify factors that lead to successful weight loss and lifestyle modification. Better understanding of these factors will facilitate successful development of tailored interventions to promote long-term maintenance of healthy weight goals.